Anti-Aging : BioCell Collagen® for Anti-aging

A key event in skin aging
    The skin is the largest organ in the body. Maintaining healthy amount of both collagen and glycosaminoglycans (GAGs, a long chain of mucopolysaccharides) such as hyaluronic acid (HA) are crucial for the dermis, which if healthy contributes to a youthful appearance. Both natural and photoaging processes cause the breakdown and loss of these molecules, which in turn leads to the disorganization of the dermal structure that generates visible aging signs such as wrinkles and fine lines as well as dehydration and scaling. This inevitable skin aging process can be delayed or counteracted by BioCell Collagen® which provides a synergy of hydrolyzed collagen and low molecular weight HA.

An innovative comprehensive solution for skin beauty
    BioCell Collagen® is a patented dietary ingredient which takes a comprehensive approach to skin beauty. It is a naturally-occurring matrix of hydrolyzed collagen type II and low molecular weight (LMW) hyaluronic acid (HA) and chondroitin sulfate, providing multi-layered mechanisms which counteract both natural and photoaging process in the skin.

    First, it contains highly absorbable building blocks of various components of skin dermis, replenishing aging-dependent loss of both collagen and GAGs. Second, BioCell Collagen® provides an additional support for the integrity and healthy levels of HA. HA plays an essential role in skin hydration by retaining water in the dermis. Daily ingestion of BioCell Collagen® (1500 mg/day) was shown to increase HA levels in the blood about 60 fold from its baseline. Additionally, BioCell Collagen® inhibits HA-degrading enzyme, hyaluronidases, helping maintain the integrity of HA. This is particularly important for counteracting photoaging because chronic UV exposure of the skin results in the heightened activity of hyaluronidase, contributing to the skin dehydration, reduced turgidity, and wrinkle generation.

Human skin study: Beauty from within effects of BioCell Collagen®
    A human skin study (2011) enrolling 26 ladies who were undergoing both natural and photoaging processes in the face demonstrated that daily ingestion of 1 g of BioCell Collagen® for 12 weeks led to a significant reduction of wrinkle counts and line depth while enhancing hydration, collagen content, and blood microcirculation. This outcome strongly suggests that the multiple actions of BioCell Collagen® synergistically antagonized skin aging process.

    It is important to note that skin collagen content (type I) increased. Considering that hydrolyzed collagen type II stimulates the biosynthesis of collagen type II, this new finding makes BioCell Collagen® a unique nutraceutical that can support both major types of collagen, the loss of which is implicated in the deterioration of connective tissues throughout the body.

A holistic approach: beauty from both inside and outside
    Many skin care brands in the market contain synthetic peptides and fermented HA which are claimed to stimulate the production of collagen and enhance skin hydration. Recently, BioCell Technology has developed BioCell Collagen® CG-WS, a cosmetic-grade formulation. It can be incorporated into topical applications together with other water or lipid soluble bioactive molecules. BioCell Collagen® CG-WS has not shown any cellular cytotoxicity or allergenicity on the human skin, which would make its combination with ingestible BioCell Collagen® a safe, natural, and holistic solution for skin health from inside and from outside.